Clinical Ventures
Finding solutions at the intersection of care delivery and healthcare coverage
Sandbox Clinical Ventures invests in innovations that improve medical care.
OUr thesis
We build partnerships between providers, payors, and entrepreneurs to accelerate improvement in care delivery. We deliver value beyond capital at all stages of innovation, from pre-approval through commercialization.
Fund focus
Stage
Seed through growth stage. We lead rounds and take board seats, and we invest both before and after regulatory approval and before and after commercialization.
Investment scope
Precision medicine, diagnostics, devices, and AI applied to diagnosis, treatment, and clinical trials. We do not invest in biotech or therapeutics.
Geography
Global, with a focus on North America, Europe, and Asia Pacific. We look to invest in companies where our Limited Partner base is active.
Curated access
Our portfolio companies work directly with payors, hospital systems, and other strategic partners to align solutions with real-world healthcare priorities and accelerate commercial growth.
Portfolio
Companies advancing how care is delivered
Big Health
Offers a digital cognitive behavioral therapy (CBT) platform addressing insomnia, generalized anxiety disorder (GAD), and depression.
Humata Health
AI-enabled prior authorization automation software platform for providers and payors.
Exited
Noctrix Health
Offers a non-invasive, drug-free device used in the treatment of restless leg syndrome (RLS).
Exited
The Sandbox Clinical Ventures Fund was formed as an affiliate of the Blue Venture Fund, which has made a commitment to co-invest in all Sandbox Clinical Venture Fund investments



